Differential electronic detector to monitor apoptosis using dielectrophoresis-induced translation of flowing cells (dielectrophoresis cytometry)
نویسندگان
چکیده
منابع مشابه
Dielectrophoresis Based Micro Flow Cytometry.
We report a simplified flow cytometer design that makes use of negative dielectrophoresis (DEP) for particle focusing and integrated optical and AC impedance detectors to enable an inexpensive, compact and robust system for cell and particle characterization. This straightforward, modular design could be applied as a standalone instrument or as a particle detector in an integrated micro total a...
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Basic IC fabrication techniques are employed in this paper with the purpose of designing a microfluidic device with a 3D electrode arrangement to separate live and dead biological cells. This is done using the concept of dielectrophoresis, which describes the transnational motion of particles due to the application of a non-uniform electrical field. The simulations where carried out using the p...
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Apoptosis, or programmed cell death, is a vital cellular process responsible for causing cells to self-terminate at the end of their useful life. Abrogation of this process is commonly linked to cancer, and rapid detection of apoptosis in vitro is vital to the discovery of new anti-cancer drugs. In this paper, we describe the application of the electrical phenomenon dielectrophoresis for detect...
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ژورنال
عنوان ژورنال: Biomicrofluidics
سال: 2013
ISSN: 1932-1058
DOI: 10.1063/1.4793223